The fonds consists of biographical material (1901-1987), teaching material (1899-1948), publications (1913-1949), lectures (1919-1945), journals/notebooks (1911-1948), correspondence/ subject files (1912-1962), Vancouver Natural History Society material (1927-1941), printed material and photographs (1919-1949).

The fonds consist of Harrison's personal and professional materials related to his career, including correspondence, laboratory notes, teaching notes, and manuscripts. The fonds is divided into four series: Professional Life series (1966-2008); Undergraduate and Graduate Education (1941-A); Correspondence series (1973-2002), and Poetry series (1966-1968). A film is also included, entitled Asymmetry and Dissipation, or, Life is so Irreversible – listed in the Archives as UBC Film # 111.